| Protocol # | Short Title | Title | Target Accrual | Actual Accrual | Status | Main Eligibility | ClinicalTrials.gov Link | |
|---|---|---|---|---|---|---|---|---|
| ATN 164 | Screen2Prevent (S2P) | Screen2Prevent (S2P): Using Digital Health to Improve HIV Screening and Prevention for Adolescents in the Emergency Department | ED: 84,000 cSHS: 280 | Pending | In Development | 14-24 years of age; Able to read and understand English | Pending | https://www.atnconnect.org/atn-164/ |
| ATN 165 | Linking Youth to PrEP Services (LYPS) | An innovative mobile delivery and mHealth intervention to optimize PrEP adherence and persistence among young gay, bisexual, and other men who have sex with men | 272 | Pending | Pending | 13-24 years of age; Assigned male sex at birth; reports has had sex with a man in the past year; and meets CDC indications for PrEP | Pending | https://www.atnconnect.org/atn-165/ |
| ATN 166 | CHOOSE | An integrated strategy of PrEP mobile health support and doxycycline PEP for young gay, bisexual, and other men who have sex with men | FG: 32 Pilot: 20 RCT: 200 | FG:12 | Enrolling | Focus Groups: 13-24 years of age; Identifies as cis-gender male; Not currently taking PrEP and interested in learning more about PrEP; Self-reports being at risk for HIV acquisition, defined as having anal or vaginal sex with a cis-gender male or transgender female in the past 6 months Technical Pilot and RCT: 13-24 years of age; Identifies as cis-gender male; Not currently taking PrEP and interested in learning more about PrEP; Self-reports being at risk for HIV acquisition, defined as having anal or vaginal sex with a cis-gender male or transgender female in the past 6 months; HIV negative within 28 days of enrollment | FG: NA Pilot: N/A RCT: Pending | https://www.atnconnect.org/atn-166/ |
| ATN 167 | Legal, Economic, and Affirming Peer Support (LEAP) | A status-neutral multicomponent intervention to improve HIV prevention and care continua outcomes among transgender and gender diverse youth | 250 | Pending | In Development | 15-24 years of age; Self-identify as a gender identity that does not correspond with the sex assigned on their original birth certificate; Self-identify as a person of color; Any condomless sex (6 months); English or Spanish speaking | Pending | https://www.atnconnect.org/atn-167/ |
| ATN 168 | HIV and Pregnancy Protection in Youth (HAPPY) | Values and Preferences for a Novel, Systemic, Injectable Multipurpose Product for HIV and Pregnancy Prevention in Individuals Assigned Female at Birth in the United States | IDI: 50 Pilot: 15 DCE: 440 | IDI: 42 | Enrolling | 15-24 years of age; Assigned female at birth; | NA | https://www.atnconnect.org/atn-168/ |
| ATN 169 | LEN BRIDGE | Safety, Tolerability, Acceptability and Pharmacokinetics of Novel, Long-Acting Injectable Lenacapavir for the Prevention of HIV among Adolescents | 60 | Pending | Protocol Development Paused | 13-17 years of age; Assigned female, male or intersex at birth and self-identify as either cisgender or transgender; Sexually active (in the last 12 months) with at least one partner assigned male at birth; Body weight ≥ 35 kg; Able to read and understand English | Pending | https://www.atnconnect.org/atn-coming-soon/ |
| ATN 170 | IMPACT | Hybrid Type 2 Effectiveness-Implementation Trial of Status Neutral, Integrated Behavioral Activation and Risk Reduction Intervention for Stimulant Use Among Sexually Active Young GBMSM | 360 | Pending | Pending | 15-24 years of age at enrollment; Self-identifies as cisgender boy or man; Resides in United States; Self-report CAS with another boy/man – receptive or insertive – while using stimulants (1 hour prior to, or during, sex) within the last 3 months | https://www.clinicaltrials.gov/study/NCT06444360 | https://www.atnconnect.org/atn-170/ |
| ATN 172 | MPT | Developing a Novel, Multipurpose Injectable Product Containing Cabotegravir (CAB) and Levonorgestrel (LNG) for Healthy, HIV-Negative Youth Assigned Female at Birth (AFAB) in the United States (US), including Transgender and Gender Diverse (TGD) Youth | 16 | Pending | Not Yet In Development | Healthy, HIV-negative adolescents and young adults AFAB, ages 18-24 years, inclusive | Pending | https://www.atnconnect.org/atn-coming-soon/ |
Abbreviations:
cSHS = Computerized Sexual Health Screen; DCE = Discrete Choice Experiment; ED = Emergency Department; FG = Focus Group; IDI = In Depth Interview; RCT = Randomized Clinical Trial